Study Links Shift Work to Risk for Type 2 Diabetes: MedlinePlus

Shift workers, especially men, may be at higher risk for type 2 diabetes compared to people not on such schedules, a new study suggests.
Also at special risk are shift workers who don’t work on a set schedule, with shifts moving around at various times of the day.
The findings are “not at all surprising,” said one expert, Dr. Alan Manevitz, a clinical psychiatrist at Lenox Hill Hospital in New York City.
“Physicians have long known that working shifts disrupts many key body chemicals, creating a ripple effect that can lead to ailments such as gastrointestinal disorders, cardiovascular disease and even cancer,” he said. “Now type 2 diabetes can be added to this considerable list.”
In the new review, researchers analyzed data from 12 international studies involving more than 226,500 people.
The study, led by Zuxun Lu of Huazhong University of Science and Technology in Wuhan, China, took several factors into account, such as workers’ shift schedules, their body mass index (BMI, a calculation of height and weight), family history of diabetes and their level of physical activity.
Although the findings weren’t able to show a direct cause-and-effect relationship, the researchers found that any amount of shift work was linked to a 9 percent greater risk for developing diabetes. Gender also played a role — for men engaged in shift work, the risk jumped to 37 percent.
Although the reason why men are at greater risk than women isn’t clear, the researchers believe that testosterone levels may play a role. Prior studies have pointed to an association between low testosterone levels and insulin resistance and diabetes, the researchers noted.
Daytime levels of this male hormone are regulated by the internal body clock, Lu’s team explained.
Those whose shifts moved around through different periods of the day were especially likely to develop type 2 diabetes than those who worked normal “office hours.” The study found rotating shift work to be linked to a 42 percent greater risk for diabetes.
According to Lu’s team, erratic working schedules make it more difficult for the body to establish a sleep-wake cycle, and poor sleep may worsen insulin resistance, a precursor to diabetes.
Previous studies have also linked shift work to weight gain and obesity, a big risk factor for type 2 diabetes. And the researchers note that shift work can also affect cholesterol levels and blood pressure.
via Study Links Shift Work to Risk for Type 2 Diabetes: MedlinePlus.
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BBC News – Global decline of wildlife linked to child slavery

New research suggests the global decline in wildlife is connected to an increase in human trafficking and child slavery.
Ecologists say the shortage of wild animals means that in many countries more labour is now needed to find food.
Children are often used to fill this need for cheap workers, especially in the fishing industry.
The decline in species is also helping the proliferation of terrorism and the destabilisation of regions.
According to a study in the journal, Science, the harvesting of wild animals from the sea and the land is worth $400bn annually and supports the livelihoods of 15% of the world’s population.
via BBC News – Global decline of wildlife linked to child slavery.

BBC News – Bedtime light ‘may stop cancer drug working’

Even low levels of light in bedrooms may stop breast cancer drugs from working, US researchers have warned.
Animal tests showed light, equivalent to that from street lamps, could lead to tumours becoming resistant to the widely used drug Tamoxifen.
The study, published in the journal Cancer Research, showed the light affected sleep hormones, which in turn altered cancer cell function.
UK experts said it was an intriguing finding, but not proven in people.
Tamoxifen has transformed the treatment of breast cancer by extending lives and increasing survival times.
It stops the female hormone oestrogen fuelling the growth of tumours although the cancerous cells may eventually become resistant to the drug.
via BBC News – Bedtime light ‘may stop cancer drug working’.

Africa – Wreckage from missing Algerian plane reportedly found: Malian TV – France 24

Debris from the Air Algérie flight that went missing over northern Mali early Thursday was reportedly found about 50 kilometers from the Mali – Burkina Faso border, according to both Malian and Burkina Faso sources.

According to Gen. Gilbert Diendere, a close aide to Burkina Faso President Blaise Compaore, the wreckage was found about 50 kilometers (31 miles) from the border of Burkina Faso near the village of Boulikessi in Mali, south of the Malian city of Gao.

Malian state television also said the wreckage was found near the village of Boulikessi, adding that President Ibrahim Boubacar Keïta is due to visit the site of the crash on Friday.

Algeria’s transport minister also said the plane’s remains had apparently been found. French officials could not confirm the discovery late Thursday night.

“We sent men with the agreement of the Mali government to the site and they found the wreckage of the plane with the help of the inhabitants of the area,” said Gen. Diendere, who is heading the crisis committee set up to investigate the flight.

“They found human remains and the wreckage of the plane totally burnt and scattered,” he said.

He told reporters that rescuers went to the area after they had heard from a resident that he saw the plane go down 80 kilometers (50 miles) southwest of Malian town of Gossi.

via Africa – Wreckage from missing Algerian plane reportedly found: Malian TV – France 24.

Contact lost with Air Algerie plane carrying 116 people from Burkina Faso | Reuters

Authorities have lost contact with an Air Algerie flight en route from Ouagadougou in Burkina Faso to Algiers with 110 passengers on board, Algeria’s APS state news agency and a Spanish airline company said on Thursday.
APS said authorities lost contact with flight AH 5017 an hour after it took off from Burkina Faso.
Spanish private airline company Swiftair confirmed it had no contact with its MD-83 aircraft operated by Air Algerie, which it said was carrying 110 passengers and six crew. An Algieran official had earlier said it was an Airbus A320.
via Contact lost with Air Algerie plane carrying 116 people from Burkina Faso | Reuters.
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